产品货号：
Z28721
中文名称：
TOLLIP抗体
英文名称：
Anti-TOLLIP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TOLLIP Antibody |
| 指标别名 | IL 1RAcPIP;toll interacting protein;TOLLIP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM |
| 基因名称 | TOLLIP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Tollip(224-243aa NAQPRCSEEDLKAIQDMFPN). |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TOLLIP(TOLL-Interacting Protein),is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene.Lo et al.(2009) stated that the TOLLIP gene maps to chromosome 11.The mouse gene maps to chromosome 7.By Western blot analysis of embryonic kidney cells,Burns et al.(2000) confirmed the binding of TOLLIP to IL1RAP,to a complex of IL1RAP-IL1R1,and to IL18R.Burns et al.(2000) proposed that IL1B stimulation induces aggregation of IL1Rs,recruitment of MYD88 followed by TOLLIP-IRAK complexes,and the phosphorylation of IRAK by MYD88.This leads to the dissociation of TOLLIP from IRAK,which can then transmit the IL1-induced signals. |
| Uniprot ID | Q9H0E2 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | toll interacting protein |
| 蛋白名全称 | Toll-interacting protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400Human- (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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